Comprehensive Biospecimen Processing Protocols

As a part of Cureline Group, CMS provides access to biospecimen acquisition ( and translational histopathology ( Animal and human preclinical and clinical Tissue Processing services will be performed in collaboration with Cureline Biopathology LLC . CBP is a translational research histopathology laboratory located in Brisbane, CA. For all human biospecimens processed through our group, we provide an H&E slide and a detailed pathology report from a US-board certified medical pathologist (additional fees apply). Animal tissue can be examined by a DVM pathologist with an extensive expertise in animal toxicology

Human and Animal Tissue Processing

  • Tissue grossing and processing (for fresh and fixed tissues)
  • Paraffin and OCT embedding (tissues and cell pellets)
  • Preparation of tissue slides (paraffin blocks, OCT blocks, frozen tissues)
  • Preparation of human tissue TMA (FFPE) from tissues and cell pellets
  • Clinical trial tissue processing (standard and custom protocols)

Human and Animal Tissue Analysis

  • H&E and special (clinical) stains
  • Immunohistochemistry (IHC), standard protocols
  • Development of custom IHC protocols using the DAKO instrumentation system
  • Digital pathology: high-resolution whole slide scan, image analysis
  • Comprehensive pathology report provided by the US board-certified MD pathologists
  • Proteomics biomarker studies


Digital imaging and analysis is available for an additional fee. We work on the 3D-Histech scanner for HD full slide tissue image and use VisioPharm or HALO software.